Phytosterols Reduce Cholesterol Absorption by Inhibition of 27-Hydroxycholesterol Generation, Liver X Receptor α Activation, and Expression of the Basolateral Sterol Exporter ATP-Binding Cassette A1 in Caco-2 Enterocytes
Author:
Affiliation:
1. Institute for Cardiovascular Prevention, University of Munich, Munich, Germany
2. Department of Pharmacy, Center for Drug Research, University of Munich, Munich, Germany
Publisher
Oxford University Press (OUP)
Subject
Nutrition and Dietetics,Medicine (miscellaneous)
Link
http://academic.oup.com/jn/article-pdf/142/6/981/23951441/981.pdf
Reference54 articles.
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2. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters;Berge;Science.,2000
3. ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion;Graf;J Biol Chem.,2003
4. Comparison of the intestinal uptake of cholesterol, plant sterols, and stanols in mice;Igel;J Lipid Res.,2003
5. Selective sterol accumulation in ABCG5/ABCG8-deficient mice;Yu;J Lipid Res.,2004
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