Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women

Author:

Yan Jian1,Jiang Xinyin1,West Allyson A1,Perry Cydne A1,Malysheva Olga V1,Brenna J Thomas1,Stabler Sally P1,Allen Robert H1,Gregory Jesse F1,Caudill Marie A1

Affiliation:

1. From the Division of Nutritional Sciences, Cornell University, Ithaca, NY (JY, XJ, AAW, OVM, JTB, and MAC); the Family & Consumer Sciences–Nutrition, Shepherd University, Shepherdstown, WV (CAP); the Department of Medicine and Division of Hematology, University of Colorado School of Medicine, Aurora, CO (SPS and RHA); and the Department of Food Science and Human Nutrition, University of Florida,

Funder

Egg Nutrition Center

National Cattlemen’s Beef Association and the Nebraska Beef Council

USDA Cooperative State Research, Education, and Extension Service

Affinito-Stewart Grants Program, through the President’s Council of Cornell Women

Publisher

Oxford University Press (OUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference29 articles.

1. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline;Food and Nutrition Board, Institute of Medicine,1998

2. MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline;Yan;Am J Clin Nutr,2011

3. Pre-and postnatal health: evidence of increased choline needs;Caudill;J Am Diet Assoc.,2010

4. Pregnancy and lactation are associated with diminished concentrations of choline and its metabolites in rat liver;Zeisel;J Nutr,1995

5. Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans;Yan;Am J Clin Nutr,2012

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