AMPing Down Leucine Action in Skeletal Muscle
Author:
Affiliation:
1. Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Evansville, IN 47712
2. Mead Johnson Nutritionals, Evansville, IN 47721
Publisher
Oxford University Press (OUP)
Subject
Nutrition and Dietetics,Medicine (miscellaneous)
Link
http://academic.oup.com/jn/article-pdf/138/12/2307/24056145/2307.pdf
Reference12 articles.
1. Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis;Drummond;Curr Opin Clin Nutr Metab Care.,2008
2. Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-β-D-ribonucleoside prevents leucine stimulated protein synthesis in rat skeletal muscle;Pruznak;J Nutr.,2008
3. Signaling pathways involved in translational control of protein synthesis in skeletal muscle by leucine;Anthony;J Nutr.,2001
4. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1;Oshiro;J Biol Chem.,2007
5. Amino acids and mTOR signalling in anabolic function;Proud;Biochem Soc Trans.,2007
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1. Comparative effects of whey protein versus l-leucine on skeletal muscle protein synthesis and markers of ribosome biogenesis following resistance exercise;Amino Acids;2015-10-27
2. l-Leucine supplemented whey protein. Dose–response effect on heart mTOR activation of sedentary and trained rats;Food Research International;2013-08
3. Effects of whey protein and casein plus leucine on diaphragm the mTOR pathway of sedentary, trained rats;Food Research International;2012-11
4. β-Hydroxy-β-methylbutyrate (HMβ) supplementation stimulates skeletal muscle hypertrophy in rats via the mTOR pathway;Nutrition & Metabolism;2011
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