Author:
Grigimalsky E. V.,Garga A. I.,Tarasov A. V.,Dovgiy I. N.,Budnyk N. N.
Abstract
Currently, HIV infection is becoming epidemic. More than 42% of HIV-infected people in the world are women of childbearing age. With the onset of antiretroviral therapy, chemoprophylaxis during pregnancy, and planned cesarean section, the risk of perinatal HIV transmission decreases to 1–2%. However, various side effects such as anemia, neutropenia, thrombocytopenia, fatty liver dystrophy, toxic hepatitis, acute pancreatitis, increased serum transaminases, changes in biochemical parameters of liver function, impaired glucose tolerance, and hypocoagulation may occur in the context of antiretroviral therapy. This poses to the anesthesiologist a number of new tasks to ensure patient safety during the perioperative period.
Publisher
Interdisciplinar Academy of Pain Medicine
Subject
Industrial and Manufacturing Engineering,Metals and Alloys,Strategy and Management,Mechanical Engineering
Reference14 articles.
1. Lorenzi P, Spicher VM, Laubereau B, Hirschel B, Kind C, Rudin C, et al. Antiretroviral therapies in pregnancy: maternal, fetal and neonatal effects. Swiss HIV Cohort Study, the Swiss Collaborative HIV and Pregnancy Study, and the Swiss Neonatal HIV Study. AIDS. 1998 Dec 24;12(18):F241-7.
2. Garcia PM. Maternal Toxicity and Pregnancy Complications in Human Immunodeficiency Virus–Infected Women Receiving Antiretroviral Therapy: PACTG 316. Yearbook of Obstetrics, Gynecology and Women’s Health [Internet]. Elsevier BV; 2006 Jan;2006:99–100. Available from: https://doi.org/10.1016/s1090-798x(08)70364-3
3. De Andrade CM, Duarte G, Quintana SM, Montes MBA, Toloi MRT. Effect of antiretroviral therapy on hemostasis in Brazilian pregnant women with HIV infection. Blood Coagulation & Fibrinolysis [Internet]. Ovid Technologies (Wolters Kluwer Health); 2007 Dec;18(8):769–74. Available from: https://doi.org/10.1097/mbc.0b013e3282f1012d
4. Fabricius EM, Schramm W, Goebel FD, Schmitz K, Patzak A, Hammel G // International Conference on AIDS. Fibrinolysis and endothelin in retinal and conjunctival microangiopathy in HIV-infection // IntConf AIDS. 2002 Jul. 19–24; 8: 77 (abstract no. PuB 7172).
5. Omoregie R, Adeghe JE, Ogefere HO, Omokaro EU, Ekeh CC. Haemorheologic and fibrinolytic activity in Nigerian HIV infected. African health sciences. 2008;8(4):217-9.