Affiliation:
1. Institute of Fine Organic Chemistry after A.L. Mnjoyan, Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia
Abstract
Производные пиридиновых солей представляют интерес как с химической, так и с фармакологической точки зрения. Обладая высокой биологической активностью, пиридины обеспечивают развитие синтеза новых систем и открытие новых потенциальных лекарств на их основе. В данной работе комплексно представлены основные исследования, проведенные в последние годы по четвертичным солям пиридина, обладающим биологической активностью. // Derivatives of pyridinium salts are of interest both from a chemical and a pharmacological point of view. Having high biological activity, pyridines ensure the development of the synthesis of new heterocyclic systems and the discovery of new potential drugs based on them.
All this will facilitate the transition to salt forms of highly active compounds. This work provides a brief overview of pyridine salts, including synthesis, nucleophilic reactivity, possible ylide-cyclic and photochemical reactions, catalysis, as well as the application spectrum and biological effects of pyridine salts as ionic liquids (PyILs). The main research conducted in recent years on quaternary pyridine salts with biological activity is comprehensively presented.
Publisher
Medical Institute after Mehrabyan