THE GROWTH-STIMULATING EFFECT OF GROWTH HORMONE AND l-THYROXINE ON THE MAMMARY GLANDS AND UTERUS OF THE MOUSE

Abstract

SUMMARY Ovariectomized mice, treated with a preparation of growth hormone (GH) containing thyrotrophic hormone (TSH), showed increased mammary duct growth and increased uterine weight. The effect of the amount of GH used was similar in mice treated either with or without oestrone. Similar mice, treated with l-thyroxine, showed increased uterine weight but no significant effect on mammary duct growth. It appears that TSH may have been responsible for the effect of GH on uterine weight but not for its effect on mammary duct growth.