β-GLUCURONIDASE ACTIVITY AFTER THYRO-PARATHYROIDECTOMY IN RATS

Abstract

SUMMARY β-Glucuronidase activity was followed in the liver, spleen, thymus, adrenals, kidneys and submaxillary glands of the rat during the atrophy of these organs caused by thyro-parathyroidectomy. The atrophy is not related, except in the case of the liver, to deficient food intake. β-Glucuronidase activity per unit weight of tissue was found to be increased in almost all the organs examined in correlation with the period of fastest loss in weight: when the rate of weight loss decreased or was reduced to nil, the enzyme levels showed a tendency to return to normal values. The significance of these data is discussed.