RESPONSES OF HYPOPHYSECTOMIZED RATS TO STRESS

Author:

BADRICK F. E.,BRIMBLECOMBE R. W.,REISS M.

Abstract

SUMMARY Rats stressed by swimming in cold water (15° C) show a considerably decreased uptake of 32P by the thyroid gland, which is comparable with the decrease in the uptake of 131I. The 32P uptake of the adrenals is increased. These changes are independent of the anterior lobe of the pituitary, since they also occur after hypophysectomy. It is assumed that they are caused by the increased production of vaso-constrictor substances, since treatment with adrenaline produced identical changes in the function of thyroid and adrenals in both intact and hypophysectomized rats. The significance of these changes in formulating a concept of the physiological reaction of the organism to conditions of stress is discussed.

Publisher

Bioscientifica

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Sozialer Stress bei Tupajas (Tupaia belangeri);Zeitschrift f�r Vergleichende Physiologie;1969

2. Metabolic stress of endurance swimming in the laboratory rat.;Journal of Applied Physiology;1967-01

3. Orientierende Übersicht;Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie;1966-12

4. Microangiographic Visualization of Blood Distribution in Intact and Regenerated Rat Adrenals Before and During Cold Stress;Angiology;1964-08

5. Endocrine Adaptive Mechanisms and the Physiologic Regulation of Population Growth;Physiological Mammalogy;1963

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