Adrenocortical development and cancer: focus on SF-1-Reference-Cited by-同舟云学术

Adrenocortical development and cancer: focus on SF-1

Published:2010-03-03 Issue:6 Volume:44 Page:301-307
ISSN:0952-5041
Container-title:Journal of Molecular Endocrinology
language:
Short-container-title:

Author:

Lalli Enzo¹¹

Affiliation:

1. 1Institut de Pharmacologie Moléculaire et CellulaireCNRS UMR 6097, 660 route des Lucioles, Sophia Antipolis, 06560 Valbonne, France2Université de NiceSophia Antipolis, 06560 Valbonne, France

Abstract

Steroidogenic factor-1 (SF-1/Ad4-binding protein; NR5A1) is an essential regulator of tissue-specific gene expression in steroidogenic cells and of adrenogonadal development. Here, I discuss recent data in the literature showing the implication of SF-1 and the importance of its dosage not only during development but also for adrenal cortex tumorigenesis in humans and mice.

Publisher

Bioscientifica

Subject

Endocrinology,Molecular Biology

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators;Journal of Biological Chemistry;2023-08

2. Steroidogenic Factor 1, a Goldilocks Transcription Factor from Adrenocortical Organogenesis to Malignancy;International Journal of Molecular Sciences;2023-02-10

3. Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells;Developmental Cell;2022-11

4. Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells;2022-11-01

5. Comprehensive Characterization of the Regulatory Landscape of Adrenocortical Carcinoma: Novel Transcription Factors and Targets Associated with Prognosis;Cancers;2022-10-27