Abstract
SUMMARY
Pituitary and plasma growth hormone were measured in foetal and weanling rats. Growth hormone was first detected in the pituitary (66 ± 8 ng) and plasma (26 ± 2 ng/ml) of 19·5-day-old foetuses. Pituitary growth hormone content increased rapidly up to the end of gestation and after birth. Plasma levels were high after 21·5 days of gestation (147 ± 8 ng/ml) and a further increase was observed at birth. The plasma growth hormone level fell to that of adult levels 5–10 days after birth. An early modulation of growth hormone secretion is discussed since newborn rats aged 2 h showed a rapid decrease in plasma levels at 25 °C while there was no such decrease in newborn animals maintained at 37 °C.
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Cited by
140 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献