LUTEINIZING HORMONE LEVELS IN PLASMA AND URINE IN WOMEN DURING NORMAL MENSTRUAL CYCLES AND IN WOMEN TAKING COMBINED CONTRACEPTIVES OR CHLORMADINONE ACETATE

Abstract

SUMMARY Radioimmunoassay measurements of luteinizing hormone (LH) levels were made in urine and plasma throughout normal menstrual cycles and cycles when either a combined oral contraceptive or low dosage continuous chlormadinone acetate were being taken by healthy young women. The typical mid-cycle ovulatory increase of LH was suppressed in the cycles when the combined contraceptive preparations were taken but was present in the majority of cycles during the administration of continuous chlormadinone acetate.