PREPARATION OF HUMAN GROWTH HORMONE

Author:

WALLACE A. L. C.,FERGUSON K. A.

Abstract

SUMMARY A simple method for the preparation of human growth hormone using chromatography on diethylaminoethyl-cellulose is described. Material prepared in this way, when assayed by growth of the tibial epiphysial cartilage in hypophysectomized rats, is at least as active as material prepared by published methods and is obtained in high yield. The only other anterior pituitary hormone activity present in any concentration is prolactin.

Publisher

Bioscientifica

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Cited by 37 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. The Chemistry of Human Pituitary Growth Hormone;Advances in Enzymology - and Related Areas of Molecular Biology;2006-11-22

2. Structure‐Function Relationships of Growth Hormone and Other Members of the Growth Hormone Gene Family;Comprehensive Physiology;1999-12

3. Stability and Characterization of Human Growth Hormone;Pharmaceutical Biotechnology;1993

4. Growth Hormone Heterogeneity: Genes, Isohormones, Variants, and Binding Proteins;Endocrine Reviews;1991-11

5. Heterogeneity of Growth Hormone;Basic and Clinical Aspects of Growth Hormone;1988

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