Use of in vitro and in vivo tests in the diagnosis of food-induced anaphylaxis

Use of in vitro and in vivo tests in the diagnosis of food-induced anaphylaxis – a case study

Published:2023-12-29 Issue:4 Volume:19 Page:419-424
ISSN:1734-1531
Container-title:Pediatria i Medycyna Rodzinna
language:
Short-container-title:Pediatr Med Rodz

Author:

Biela-Mazur Jadwiga¹^ORCID,Czyżewska-Dudek Anna¹,Jazgarska Paulina²

Affiliation:

1. Department of Allergology and Pneumonology, Institute of Tuberculosis and Lung Diseases, Rabka-Zdrój, Poland

2. Department of Paediatrics, Independent Public Health Care Centre in Lubartów, Lubartów, Poland

Abstract

Food allergy is a chronic disease that affects both children and adults. Systemic allergic reactions in children are most commonly caused by foods, especially nuts, milk, and eggs. A conventional diagnostic work-up for allergy typically pinpoints the allergen source, while component-resolved diagnostics is an approach that identifies the allergen molecules responsible for causing anaphylaxis. In some cases, determining the causative agent of anaphylaxis requires the use of various diagnostic tests. In the following paper, we want to highlight the importance of a critical approach to allergy tests results and caution in the diagnosis of idiopathic anaphylaxis. Based on a case report of food-induced anaphylaxis, we discuss the diagnostic methods that can be applied following a negative IgE test result for allergens obtained with a multiplex platform.

Publisher

Medical Communications Sp. z.o.o.

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