Quantitative ultrasonography as a tool for the evaluation of breast tumor response
to neoadjuvant chemotherapy
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Published:2022-04-13
Issue:89
Volume:22
Page:86-92
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ISSN:2084-8404
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Container-title:Journal of Ultrasonography
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language:
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Short-container-title:J Ultrason
Author:
Piotrzkowska-Wróblewska Hanna, ,Dobruch-Sobczak Katarzyna,Litniewski Jerzy, ,
Abstract
Neoadjuvant chemotherapy is increasingly becoming the first treatment step in
breast cancer. Despite the enormous advantages of this therapy, it is a method
characterized by a high level of toxicity and thus carries a huge burden for the
patient. Therefore, it is highly desirable to begin monitoring the patient’s response to
treatment at an earlier stage. Currently, apart from traditional imaging methods, a
completely new technique (in the context of monitoring the outcomes of chemotherapy),
called quantitative ultrasound, is gaining popularity. It is a method based on the exact
same ultrasound echoes as in traditional ultrasound imaging. The innovative approach of
the method is that these echoes are not used for visualization but to characterize the
condition of the tissue by parameterizing it with the aid of ultrasound biomarkers. The
biomarkers make it possible to assess the state of the tissue at the microscopic level,
and thus evaluate changes occurring in the tissue under the influence of treatment at a
very early treatment stage. The present paper aims to familiarize the reader with the
physical foundations of this method as well as present the latest results of related
research.
Publisher
Medical Communications Sp. z.o.o.
Subject
Radiology, Nuclear Medicine and imaging,Radiological and Ultrasound Technology