Affiliation:
1. Federal University of ABC (UFABC), Brazil. Dante Pazzanese Institute of Cardiology - University of São Paulo (IDPC-USP), Brazil.
2. Dante Pazzanese Institute of Cardiology - University of São Paulo (IDPC-USP), Brazil.
3. Federal University of ABC (UFABC), Brazil.
Abstract
Stents are devices with important applications in cardiology. They can be used in different cases, as coronary artery disease, peripheral interventions, such as the iliac and carotid arteries, and in very specific applications, as congenital heart disease in aortic coarctation. Studies point to biodegradability of stents as one of the main properties of future generations of these devices. The development of stents made from fully bioresorbable polymeric materials, with appropriate mechanical properties for different applications, is considered an interesting point to be studied. Thus, the objective of this project was to study models of bioabsorbable stents of poly (-L-lactic acid) (PLLA), poly (-LD lactic acid) (PLDLA) produced by additive manufacturing. The mechanical performances were evaluated by stress and tensile strain tests of different blends compositions of these materials. A heatshock shape memory allocation process and a flexible tube model for simulating implant conditions were developed. PLLA has higher mechanical strength and hardness, while PLDLA is more elastic. Thus, it was possible to study the adequacy of the composition and mechanical properties of the prototypes for each different situation studied (coronary, peripheral and Aortic coarctation implants).
Reference41 articles.
1. Abizaid A C. Stents Farmacológicos: Avanços e Perspectivas. Novas Plataformas e Stents
2. Bioabsorvíveis; a Questão do Polímero e Novos Fármacos. Tese de livre docência apresentada à Universidade de São Paulo –SP 2011.
3. Abizaid A, Ribamar Costa R J Jr, Bartorelli AL, Whitbourn R, van Geuns RJ, Chevalier B, Patel T, Seth A, Stuteville M, Dorange C, Cheong WF, Sudhir K,Serruys PW; The ABSORB EXTEND study: preliminary report of the twelve-month clinical outcomes in the first 512 patients enrolled. EuroIntervention. Apr;10(12):1396-401. doi: 10.4244/EIJV10I12A243, 2015.
4. Abu-Assi E, Castiñeira-Busto M, González-Salvado V, Raposeiras- Roubin S, Riziq-Yousef
5. Abumuaileq R, Peña-Gil C, Rigueiro-Veloso P, Ocaranza R, García-Acuña JM, GonzálezJuanatey JR. Coronary Artery Dominance and Long-term Prognosis in Patients With ST-segment Elevation Myocardial Infarction Treated With Primary Angioplasty. Rev Esp Cardiol (Engl Ed). pii: S1885-5857(15)00217-0. doi: 10.1016/j.rec.2015.04.010, 2015.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Seis anos da TASJ em perspectiva;The Academic Society Journal;2022-06-01