MpdzNull Allele in an Avian Model of Retinal Degeneration and Mutations in Human Leber Congenital Amaurosis and Retinitis Pigmentosa

Author:

Ali Manir1,Hocking Paul M.2,McKibbin Martin3,Finnegan Sorcha4,Shires Mike5,Poulter James A.1,Prescott Katrina6,Booth Adam7,Raashid Yasmin8,Jafri Hussain9,Ruddle Jonathan B.10,Mackey David A.11,Jacobson Samuel G.12,Toomes Carmel1,Lester Douglas H.13,Burt David W.2,Curry William J.4,Inglehearn Chris F.1

Affiliation:

1. From the Sections of Ophthalmology and

2. Division of Genetics and Genomics, The Roslin Institute and Royal School of Veterinary Studies, University of Edinburgh, Midlothian, United Kingdom;

3. the Eye Department, St. James's University Hospital, Leeds, United Kingdom;

4. Centre for Vision Sciences, Institute of Clinical Science, Queen's University of Belfast, Belfast, Northern Ireland, United Kingdom;

5. Pathology, Leeds Institute of Molecular Medicine, and

6. Department of Clinical Genetics, Chapel Allerton Hospital, Leeds, United Kingdom;

7. From the Sections of Ophthalmology and 7Peninsula Medical School, Plymouth, United Kingdom;

8. Department of Obstetrics and Gynaecology, King Edward Medical University, Lahore, Pakistan;

9. Gene Tech Lab 146/1, Lahore, Pakistan;

10. Department of Ophthalmology, University of Melbourne, Melbourne, Australia;

11. Lions Eye Institute, University of Western Australia, Perth, Australia;

12. Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania; and

13. Molecular Vision Group, School of Contemporary Sciences, University of Abertay, Dundee, United Kingdom.

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

General Medicine

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