1. Department of Ophthalmology, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, Japan 2Department of Ophthalmology, Itoh Clinic, Minuma-ku, Saitama City, Saitama, Japan
2. Research and Development Division, Santen Pharmaceutical Co. Ltd., Kita-ku, Osaka, Japan
3. Department of Ophthalmology, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, Japan
4. Inouye Eye Hospital, Chiyoda-ku, Tokyo, Japan 5Miyata Eye Hospital, Miyakonojo City, Miyazaki, Japan