1. From the Research and Development Division, Santen Pharmaceutical Co. Ltd., Nara, Japan; the
2. From the Research and Development Division, Santen Pharmaceutical Co. Ltd., Nara, Japan; the2Department of Biofunctional Molecules, Gifu Pharmaceutical University, Gifu, Japan; the
3. Eye Clinic, Saitama Red Cross Hospital, Saitama, Japan; and the
4. Department of Ophthalmology, Tokyo University School of Medicine, Tokyo, Japan.