Complement Factor C3a Alters Proteasome Function in Human RPE Cells and in an Animal Model of Age-Related RPE Degeneration

Author:

Ramos de Carvalho J. Emanuel1,Klaassen Ingeborg1,Vogels Ilse M. C.1,Schipper-Krom Sabine2,van Noorden Cornelis J. F.3,Reits Eric2,Gorgels Theo G. M. F.4,Bergen Arthur A. B.4,Schlingemann Reinier O.5

Affiliation:

1. Ocular Angiogenesis Group, Departments of Ophthalmology and Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

2. Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

3. Ocular Angiogenesis Group, Departments of Ophthalmology and Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands 2Department of Cell Biology and Histology, Academic Medical Center, University of Amsterda

4. Netherlands Institute for Neuroscience (NIN), Royal Academy of Sciences (KNAW), Amsterdam, The Netherlands

5. Ocular Angiogenesis Group, Departments of Ophthalmology and Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands 3Netherlands Institute for Neuroscience (NIN), Royal Academy of Sciences (KNAW), Amsterdam

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

General Medicine

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