Zfp503/Nlz2 Is Required for RPE Differentiation and Optic Fissure Closure

Author:

Boobalan Elangovan1,Thompson Amy H.1,Alur Ramakrishna P.1,McGaughey David M.1,Dong Lijin2,Shih Grace1,Vieta-Ferrer Emile R.1,Onojafe Ighovie F.1,Kalaskar Vijay K.1,Arno Gavin34,Lotery Andrew J.5,Guan Bin6,Bender Chelsea6,Memon Omar7,Brinster Lauren8,Soleilhavoup Clement9,Panman Lia9,Badea Tudor C.101112,Minella Andrea13,Lopez Antonio Jacobo14,Thomasy Sara M.1314,Moshiri Ala14,Blain Delphine1,Hufnagel Robert B.6,Cogliati Tiziana1,Bharti Kapil7,Brooks Brian P.1

Affiliation:

1. Pediatric, Developmental & Genetic Ophthalmology Section, Ophthalmic Genetics & Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States

2. Mouse Genetic Engineering Core, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States

3. University College London Institute of Ophthalmology, London, United Kingdom

4. Moorfields Eye Hospital, London, United Kingdom

5. Faculty of Medicine, University of Southampton, Southampton, United Kingdom

6. Ophthalmic Genetics Laboratory, Ophthalmic Genetics & Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States

7. Ocular and Stem Cell Translational Research Section, Ophthalmic Genetics & Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States

8. Division of Veterinary Resources, Office of Research Services, National Institutes of Health, Bethesda, Maryland, United States

9. MRC Toxicology Unit, University of Cambridge, Leicester, United Kingdom

10. Retinal Circuit Development and Genetics Unit, Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States

11. Research and Development Institute, Transilvania University of Brașov, Brașov, Romania

12. National Center for Brain Research, ICIA, Romanian Academy, Bucharest, România

13. Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California–Davis, Davis, California, United States

14. Department of Ophthalmology and Vision Science, School of Medicine, University of California–Davis, Davis, California, United States

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

General Medicine

Reference73 articles.

1. Eye morphogenesis and patterning of the optic vesicle;Fuhrmann;Curr Top Dev Biol,2010

2. Genes and pathways in optic fissure closure;Patel;Semin Cell Dev Biol,2019

3. The optic fissure in the normal and microphthalmic mouse;Hero;Exp Eye Res,1989

4. The genetic architecture of microphthalmia, anophthalmia and coloboma;Williamson;Eur J Med Genet,2014

5. CHARGE syndrome: a review;Hsu;J Paediatr Child Health,2014

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