Preclinical Evaluation of Trabectedin in Combination With Targeted Inhibitors for Treatment of Metastatic Uveal Melanoma

Author:

Glinkina Kseniya1,Nemati Fariba2,Teunisse Amina F. A. S.1,Gelmi Maria Chiara3,Etienne Vesnie2,Kuipers Muriel J.1,Alsafadi Samar4,Jager Martine J.3,Decaudin Didier25,Jochemsen Aart G.1

Affiliation:

1. Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands

2. Laboratory of Preclinical Investigation, Department of Translational Research, Institut Curie, PSL University, Paris, France

3. Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands

4. Uveal Melanoma Translational Group, Department of Translational Research, Institut Curie, PSL University, Paris, France

5. Department of Medical Oncology, Institut Curie, PSL University, Paris, France

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

General Medicine

Reference78 articles.

1. Incidence of uveal melanoma in Europe;Virgili;Ophthalmology,2007

2. Metastasis rates and sites after treatment for choroidal melanoma by proton beam irradiation or by enucleation;Koutsandrea;Clin Ophthalmol,2008

3. Screening for metastasis from choroidal melanoma: the Collaborative Ocular Melanoma Study Group Report 23;Diener-West;J Clin Oncol,2004

4. Hyperthermic isolated hepatic perfusion using melphalan for patients with ocular melanoma metastatic to liver;Alexander;Clin Cancer Res,2003

5. Isolated hepatic perfusion with high-dose melphalan for the treatment of uveal melanoma metastases confined to the liver;Noter;Melanoma Res,2004

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