Deletion of Protein Phosphatase 2A Accelerates Retinal Degeneration in GRK1- and Arr1-Deficient Mice-Reference-Cited by-同舟云学术

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Deletion of Protein Phosphatase 2A Accelerates Retinal Degeneration in GRK1- and Arr1-Deficient Mice

Published:2022-07-21 Issue:8 Volume:63 Page:18
ISSN:1552-5783
Container-title:Investigative Opthalmology & Visual Science
language:en
Short-container-title:Invest. Ophthalmol. Vis. Sci.

Author:

Kolesnikov Alexander V.¹,Luu Jennings¹²,Jin Hui²,Palczewski Krzysztof¹³⁴⁵,Kefalov Vladimir J.¹³

Affiliation:

1. Gavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, California, United States

2. Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States

3. Department of Physiology & Biophysics, University of California, Irvine, California, United States

4. Department of Chemistry, University of California, Irvine, California, United States

5. Department of Molecular Biology and Biochemistry, University of California, Irvine, California, United States

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

General Medicine

Reference41 articles.

1. Piecing together the timetable for visual transduction with transgenic animals;Makino;Curr Opin Neurobiol,2003

2. Sequential phosphorylation of rhodopsin at multiple sites;Ohguro;Biochemistry,1993

3. Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase;Chen;Proc Natl Acad Sci USA,1999

4. Prolonged photoresponses in transgenic mouse rods lacking arrestin;Xu;Nature,1997

5. Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments;Wilden;Proc Natl Acad Sci USAm,1986

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1. Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition;Proceedings of the National Academy of Sciences;2023-05

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