Rare Genetic Variants in Complement Factor I Lead to Low FI Plasma Levels Resulting in Increased Risk of Age-Related Macular Degeneration

Author:

Hallam Thomas M.123,Marchbank Kevin J.12,Harris Claire L.12,Osmond Clive4,Shuttleworth Victoria G.12,Griffiths Helen3,Cree Angela J.3,Kavanagh David12,Lotery Andrew J.3

Affiliation:

1. Complement Therapeutics Research Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom

2. National Renal Complement Therapeutics Centre, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom

3. Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom

4. MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

General Medicine

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