1. From the Angiogenesis and Laser Laboratory, Retina Research Institute, Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts;
2. Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts;
3. BioMarin Pharmaceuticals, Novato, California; and the
4. Department of Safety Assessment, Genentech, Inc., South San Francisco, California.