1. From the Department of Experimental and Clinical Pharmacology, School of Medicine, University of Catania, Catania, Italy;
2. Global Preclinical R&D Bausch & Lomb, Rochester, New York;
3. IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy; and the
4. IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy; and the4Department of Clinical and Experimental Medicine and Pharmacology, School of Medicine, University of Messina, Messina, Italy.