Lanosterol Synthase Prevents EMT During Lens Epithelial Fibrosis Via Regulating SREBP1

Author:

Ma Pengjuan1,Huang Jingqi1,Chen Baoxin1,Huang Mi1,Xiong Lang1,Chen Jieping1,Huang Shan1,Liu Yizhi1

Affiliation:

1. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

Cardiology and Cardiovascular Medicine

Reference48 articles.

1. Cataracts;Cicinelli;Lancet,2022

2. The lens epithelium as a major determinant in the development, maintenance, and regeneration of the crystalline lens;Liu;Prog Retin Eye Res,2022

3. Myofibroblast transdifferentiation: the dark force in ocular wound healing and fibrosis;Shu;Prog Retin Eye Res,2017

4. Fibrosis in the lens. Sprouty regulation of TGFbeta-signaling prevents lens EMT leading to cataract;Lovicu;Exp Eye Res,2016

5. TGFbeta pathobiology in the eye;Saika;Lab Invest,2006

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