Intravitreal Short-Hairpin RNA Attenuated Adeno-Associated Virus–Induced Knockdown of Amphiregulin and Axial Elongation in Experimental Myopia

Author:

Dong Li123,Zhang Rui-Heng123,Wu Hao-Tian123,Li He-Yan123,Zhou Wen-Da123,Shi Xu-Han123,Yu Chu-Yao123,Li Yi-Tong123,Li Yi-Fan123,Jonas Jost B.45,Wei Wen-Bin123

Affiliation:

1. Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Tongren Hospital, Capital Medical University, Beijing, China

2. Beijing Ophthalmology & Visual Sciences Key Lab, Beijing Tongren Hospital, Capital Medical University, Beijing, China

3. Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, Beijing, China

4. Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

5. Institute of Molecular and Clinical Ophthalmology Basel, Switzerland

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

General Medicine

Reference36 articles.

1. Molecular mechanisms of muscarinic receptors in mouse scleral fibroblasts: Prior to and after induction of experimental myopia with atropine treatment;Barathi;Mol Vis,2011

2. Association of IGF1 single-nucleotide polymorphisms with myopia in Chinese children;Cheng;PeerJ,2020

3. Five-year clinical trial on atropine for the treatment of myopia 2: Myopia control with atropine 0.01% eye drops;Chia;Ophthalmology,2016

4. Effects of direct intravitreal dopamine injections on the development of lid-suture induced myopia in rabbits;Gao;Graefes Arch Clin Exp Ophthalmol,2006

5. Effects of dopaminergic agents on progression of naturally occurring myopia in albino guinea pigs (Cavia porcellus);Jiang;Invest Ophthalmol Vis Sci,2014

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