High-Resolution Homozygosity Mapping Is a Powerful Tool to Detect Novel Mutations Causative of Autosomal Recessive RP in the Dutch Population

Author:

Collin Rob W. J.1,van den Born L. Ingeborgh2,Klevering B. Jeroen3,de Castro-Miró Marta4,Littink Karin W.5,Arimadyo Kentar4,Azam Maleeha6,Yazar Volkan4,Zonneveld Marijke N.4,Paun Codrut C.4,Siemiatkowska Anna M.4,Strom Tim M.7,Hehir-Kwa Jayne Y.8,Kroes Hester Y.9,de Faber Jan-Tjeerd H. N.2,van Schooneveld Mary J.10,Heckenlively John R.11,Hoyng Carel B.3,den Hollander Anneke I.1,Cremers Frans P. M.12

Affiliation:

1. From the Departments of Human Genetics and 2Ophthalmology and the 3Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands;

2. The Rotterdam Eye Hospital, Rotterdam, The Netherlands;

3. Ophthalmology and

4. From the Departments of Human Genetics and

5. From the Departments of Human Genetics and 5The Rotterdam Eye Hospital, Rotterdam, The Netherlands;

6. From the Departments of Human Genetics and the 6Department of Biosciences, COMSATS (Commission on Science and Technology for Sustainable Development in the South) Institute of Information Technology, Islamabad, Pakistan;

7. the Institute of Human Genetics, Helmholtz Zentrum Munchen, Neuherberg, Germany;

8. From the Departments of Human Genetics and the 3Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands;

9. the Department of Medical Genetics, University Medical Centre Utrecht, Utrecht, The Netherlands;

10. the Netherlands Institute of Neuroscience, Amsterdam, The Netherlands; the 10Academic Medical Centre, Amsterdam, The Netherlands; and

11. the Department of Ophthalmology and Visual Sciences, Medical School, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan.

12. From the Departments of Human Genetics and the 3Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; the 6Department of Biosciences, COMSATS (Commission on Science and Technology for Sustainab

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

General Medicine

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