Specialist α-tubulins for pluralist microtubules-Reference-Cited by-同舟云学术

Specialist α-tubulins for pluralist microtubules

Published:2021-11-11 Issue:12 Volume:220 Page:
ISSN:0021-9525
Container-title:Journal of Cell Biology
language:en
Short-container-title:

Author:

Moore Jeffrey K.¹^ORCID,Wethekam Linnea¹

Affiliation:

1. Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO

Abstract

α- and β-tubulins are encoded by multigene families, but the role of tubulin diversity for microtubule function has been a longstanding mystery. A new study (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202010155) shows that the two budding yeast α-tubulins have distinct roles during mitotic spindle positioning.

Publisher

Rockefeller University Press

Subject

Cell Biology

Link

https://rupress.org/jcb/article-pdf/doi/10.1083/jcb.202110038/1425537/jcb_202110038.pdf

Reference8 articles.

1. Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

2. Five mouse tubulin isotypes and their regulated expression during development.

3. Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes

4. The testis-specific β-tubulin subunit in drosophila melanogaster has multiple functions in spermatogenesis

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