Neuronal GDPGP1 and glycogen metabolism: friend or foe?-Reference-Cited by-同舟云学术

Neuronal GDPGP1 and glycogen metabolism: friend or foe?

Published:2020-01-23 Issue:2 Volume:219 Page:
ISSN:0021-9525
Container-title:Journal of Cell Biology
language:en
Short-container-title:

Author:

Singhal Neel S.¹²^ORCID,Lee Evan M.²,Ma Dengke K.²³^ORCID

Affiliation:

1. Department of Neurology, University of California, San Francisco, San Francisco, CA

2. Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA

3. Department of Physiology, University of California, San Francisco, San Francisco, CA

Abstract

The adult brain consumes glucose for energy needs and stores glucose as glycogen mainly in astrocytes. Schulz et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201807127) identify the stress-regulated metabolic enzyme GDPGP1 that promotes neuronal survival likely through glycogen reserves in mouse and C. elegans neurons.

Funder

National Institutes of Health

Innovative Genomics Institute

Publisher

Rockefeller University Press

Subject

Cell Biology

Link

http://rupress.org/jcb/article-pdf/doi/10.1083/jcb.202001006/1397035/jcb_202001006.pdf

Reference10 articles.

1. The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival

2. Glycogen distribution in the microwave‐fixed mouse brain reveals heterogeneous astrocytic patterns

3. A DISTINCT FORM OF ADULT POLYGLUCOSAN BODY DISEASE WITH MASSIVE INVOLVEMENT OF CENTRAL AND PERIPHERAL NEURONAL PROCESSES AND ASTROCYTES

4. Deleterious effects of neuronal accumulation of glycogen in flies and mice

5. Glycogen, its transient occurrence in neurons of the rat CNS during normal postnatal development

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