Affiliation:
1. Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115
Abstract
The proapoptotic members of the Bcl-2 family have been proposed to participate in the formation of a channel that releases these apoptogenic factors when mitochondria receive apoptotic signals. A recent study provides the first direct, biophysical measurement of a potentially apoptosis-specific mitochondrial channel, which is regulated by Bcl-2 family members and may play a primary role in the release of the proapoptotic factors.
Publisher
Rockefeller University Press
Cited by
40 articles.
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