Lipid droplets go nuclear

Author:

Farese Robert V.123,Walther Tobias C.1243

Affiliation:

1. Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115

2. Department of Cell Biology, Harvard Medical School, Harvard University, Boston, MA 02115

3. Broad Institute of MIT and Harvard, Cambridge, MA 02142

4. Howard Hughes Medical Institute, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115

Abstract

Lipid droplets (LDs) are sometimes found in the nucleus of some cells. In this issue, Ohsaki et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201507122) show that the nuclear membrane, promyelocytic leukemia bodies, and the protein PML-II play a role in nuclear LD formation, suggesting functional relationships between these structures.

Publisher

Rockefeller University Press

Subject

Cell Biology

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