Affiliation:
1. From the Department of Pathology, Washington University, School of Medicine, St. Louis, Missouri 63110.
Abstract
Beta granules isolated from rat islets of Langerhans and subjected only to phosphotungstic acid had, in negatively stained images, a 50-A periodicity. This periodicity was also observed in thin-section profiles of beta granules in intact cells. In shadowed preparations, the granules were spherical in shape and had irregular edges and surface structure. The presence of such a periodicity in the beta granule indicates that its matrix may be composed of a crystalline material.
Publisher
Rockefeller University Press
Cited by
121 articles.
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