Uniform nomenclature for the mitochondrial contact site and cristae organizing system

Author:

Pfanner Nikolaus11,van der Laan Martin11,Amati Paolo2,Capaldi Roderick A.3,Caudy Amy A.44,Chacinska Agnieszka5,Darshi Manjula6,Deckers Markus7,Hoppins Suzanne8,Icho Tateo9,Jakobs Stefan1011,Ji Jianguo12,Kozjak-Pavlovic Vera13,Meisinger Chris11,Odgren Paul R.14,Park Sang Ki15,Rehling Peter711,Reichert Andreas S.1616,Sheikh M. Saeed17,Taylor Susan S.666,Tsuchida Nobuo18,van der Bliek Alexander M.19,van der Klei Ida J.20,Weissman Jonathan S.2121,Westermann Benedikt22,Zha Jiping23,Neupert Walter24,Nunnari Jodi25

Affiliation:

1. Institut für Biochemie und Molekularbiologie, Zentrum für Biochemie und Molekulare Zellforschung, and BIOSS Centre for Biological Signalling Studies, Universität Freiburg, 79104 Freiburg, Germany

2. Pasteur Institute of Rome, University of Rome at Sapienza, 00161 Rome, Italy

3. Metabolic Profiling, Inc., Eugene, OR 97401

4. Donnelly Centre for Cellular and Biomolecular Research and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada

5. The International Institute of Molecular and Cell Biology, 02-109 Warsaw, Poland

6. Howard Hughes Medical Institute, Department of Pharmacology, and Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093

7. Department of Biochemistry II, University of Göttingen, 37073 Göttingen, Germany

8. Department of Biochemistry, University of Washington, Seattle, WA 98195

9. Somechi Orchid Laboratory, Chofu, Tokyo 182-0023, Japan

10. Department of Neurology, University Medical Center, 37075 Göttingen, Germany

11. Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany

12. The National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing, P.R. China 100871

13. Department of Microbiology, Biocenter, University of Würzburg, 97074 Würzburg, Germany

14. Department of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA 01655

15. Department of Life Sciences, Pohang University of Science and Technology, Pohang 790-784, South Korea

16. Mitochondrial Biology, Buchmann Institute for Molecular Life Sciences and Centre for Molecular Medicine, Goethe University, 60438 Frankfurt am Main, Germany

17. Department of Pharmacology, State University of New York Upstate Medical University, Syracuse, NY 13210

18. Department of Molecular Cellular Oncology and Microbiology, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8549, Japan

19. Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095

20. Molecular Cell Biology, University of Groningen, 9700 CC Groningen, Netherlands

21. Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158

22. Zellbiologie, Universität Bayreuth, 95440 Bayreuth, Germany

23. Crown Bioscience, Inc., Taicang City, Jiangsu Province, P.R. China 215400

24. Abteilung für Zelluläre Biochemie, Max-Planck-Institut für Biochemie, 82152 Martinsried, Germany

25. Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA 95616

Abstract

The mitochondrial inner membrane contains a large protein complex that functions in inner membrane organization and formation of membrane contact sites. The complex was variably named the mitochondrial contact site complex, mitochondrial inner membrane organizing system, mitochondrial organizing structure, or Mitofilin/Fcj1 complex. To facilitate future studies, we propose to unify the nomenclature and term the complex “mitochondrial contact site and cristae organizing system” and its subunits Mic10 to Mic60.

Publisher

Rockefeller University Press

Subject

Cell Biology

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