Regulation of EGFR surface levels by COPII-dependent trafficking-Reference-Cited by-同舟云学术

Regulation of EGFR surface levels by COPII-dependent trafficking

Published:2016-11-08 Issue:4 Volume:215 Page:441-443
ISSN:0021-9525
Container-title:Journal of Cell Biology
language:en
Short-container-title:

Author:

Farhan Hesso¹

Affiliation:

1. Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, 0372 Oslo, Norway

Abstract

Cell surface levels of epidermal growth factor receptors (EGFRs) are thought to be controlled mainly by endocytic trafficking, with biosynthetic EGFR trafficking presumed to be a constitutive and unregulated process. However, Scharaw et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201601090) demonstrate a role for inducible COPII trafficking in controlling EGFR surface levels.

Publisher

Rockefeller University Press

Subject

Cell Biology

Link

http://rupress.org/jcb/article-pdf/215/4/441/1373125/jcb_201611014.pdf

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