Importin-11 keeps PTEN safe from harm
Author:
Affiliation:
1. Institute of Biological Chemistry, Biophysics and Bioengineering, Heriot Watt University, Edinburgh, EH14 4AS, Scotland, UK
Abstract
Publisher
Rockefeller University Press
Subject
Cell Biology
Link
http://rupress.org/jcb/article-pdf/216/3/539/1374784/jcb_201612014.pdf
Reference14 articles.
1. The chaperone-assisted E3 ligase C terminus of Hsc70-interacting protein (CHIP) targets PTEN for proteasomal degradation;Ahmed;J. Biol. Chem.,2012
2. The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein;Chen;J. Cell Biol.,2017
3. Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors;Gimm;Am. J. Pathol.,2000
4. Controlling PTEN (phosphatase and tensin homolog) stability: A dominant role for lysine 66;Gupta;J. Biol. Chem.,2016
5. RFP-mediated ubiquitination of PTEN modulates its effect on AKT activation;Lee;Cell Res.,2013
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