Calling long distance: Cell cycle–dependent Ca2+ flows connect stem cells across regeneration tissues-Reference-Cited by-同舟云学术

Calling long distance: Cell cycle–dependent Ca2+ flows connect stem cells across regeneration tissues

Published:2023-06-14 Issue:7 Volume:222 Page:
ISSN:0021-9525
Container-title:Journal of Cell Biology
language:en
Short-container-title:

Author:

Goranci-Buzhala Gladiola¹,Niessen Carien M.¹^ORCID

Affiliation:

1. Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, University of Cologne 1 Department Cell Biology of the Skin, Cologne Excellence Cluster for Stress Responses in Ageing-associated Diseases (CECAD), , Cologne, Germany

Abstract

How adult stem cells signal in vivo over time to coordinate their fate and behavior across self-renewing tissues remains a challenging question. In this issue, Moore et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202302095) combine high-resolution live imaging in mice with machine learning tools to reveal temporally regulated tissue-scale patterns of Ca2+ signaling orchestrated by cycling basal stem cells of the skin epidermis.

Funder

Deutsche Forschungsgemeinschaft

Germany´s Excellence Strategy

Center for Molecular Medicine Cologne, University of Cologne

Publisher

Rockefeller University Press

Subject

Cell Biology

Link

https://rupress.org/jcb/article-pdf/doi/10.1083/jcb.202305022/1453483/jcb_202305022.pdf

Reference11 articles.

1. Cell cycle controls long-range calcium signaling in the regenerating epidermis

2. Homeostatic Epidermal Stem Cell Self-Renewal Is Driven by Local Differentiation

3. Capturing Spatiotemporal Signaling Patterns in Cellular Data with Geometric Scattering Trajectory Homology

4. Visualizing structure and transitions in high-dimensional biological data

5. Calcium spikes, waves and oscillations in a large, patterned epithelial tissue