Molding a PI(3,5)P2 biosensor

Author:

Weckerly Claire C.1,Hammond Gerald R.V.1ORCID

Affiliation:

1. University of Pittsburgh School of Medicine 1 Department of Cell Biology, , Pittsburgh, PA, USA

Abstract

The lipid phosphatidylinositol 3,5-bisphosphate—PI(3,5)P2—is known to be a key regulator of cellular traffic in health and disease, but its cellular localization was somewhat enigmatic until now, with the discovery of a new PI(3,5)P2 biosensor reported in this issue of JCB by Vines et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202209077).

Funder

National Institute of General Medical Sciences

National Heart, Lung, and Blood Institute

Publisher

Rockefeller University Press

Subject

Cell Biology

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