A new player in the biogenesis of lysosome-related organelles-Reference-Cited by-同舟云学术

A new player in the biogenesis of lysosome-related organelles

Published:2024-09-11 Issue:10 Volume:223 Page:
ISSN:0021-9525
Container-title:Journal of Cell Biology
language:en
Short-container-title:

Author:

Shi Anbing¹²^ORCID

Affiliation:

1. School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology 1 Department of Biochemistry and Molecular Biology, , Wuhan, China

2. Cell Architecture Research Center, Huazhong University of Science and Technology 2 , Wuhan, China

Abstract

How are Rab GTPases regulated during lysosome-related organelle (LRO) biogenesis? Li et al. (https://doi.org/10.1083/jcb.202402016) identify LYSMD proteins as crucial activators of Rab32-family GTPases in LRO development, shedding light on the previously ambiguous mechanisms governing Rab functionality in this process.

Funder

National Natural Science Foundation of China

Publisher

Rockefeller University Press

Link

https://rupress.org/jcb/article-pdf/doi/10.1083/jcb.202407194/1932262/jcb_202407194.pdf

Reference10 articles.

2. The road to lysosome‐related organelles: Insights from Hermansky‐Pudlak syndrome and other rare diseases

3. Caenorhabditis elegansHOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1

4. Modular metabolite assembly in Caenorhabditis elegans depends on carboxylesterases and formation of lysosome-related organelles