Affiliation:
1. (From the Departments of Medicine and of Dermatology of the Massachusetts General Hospital and Harvard Medical School, Boston, and the Department of Biology, Massachusetts Institute of Technology, Cambridge)
Abstract
Vitrosin, a fibrous protein obtained from the vitreous humor of the eye in the form of an indefinitely long fibril about 100 to 150 A in diameter, has been identified as a member of the collagen class of proteins. It is characterized by the collagen wide-angle x-ray diffraction pattern, and axial periodicity of about 640 A determined by electron microscopy and small-angle x-ray diffraction, an amino acid pattern characteristic of collagen as determined by paper chromatography, and a hydroxyproline and glycine content also typical of collagen. The glycine-hydroxyproline ratio is somewhat lower than that for most vertebrate collagens.
Publisher
Rockefeller University Press
Cited by
57 articles.
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