THE EFFECT OF THYMIDINE ON THE DURATION OF G1 IN CHINESE HAMSTER CELLS

Author:

Tobey R. A.1,Anderson E. C.1,Petersen D. F.1

Affiliation:

1. From the Biomedical Research Group, Los Alamos Scientific Laboratory, University of California, Los Alamos, New Mexico 87544

Abstract

The generation time of a Chinese hamster cell line was varied by the use of different lots of sera in the culture media. Analysis of the division waves following thymidine synchronization showed that lengthening of the generation time was a result of an increase in duration of the G1 phase and that thymidine treatment reduced the duration of G1 back to its minimum value.

Publisher

Rockefeller University Press

Subject

Cell Biology

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