A System of Photocatalysis for NAD+ Regeneration of Product of (S)-1-Pheylethanol by Enzymic Catalysis
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Published:2019-08-01
Issue:2
Volume:14
Page:421
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ISSN:1978-2993
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Container-title:Bulletin of Chemical Reaction Engineering & Catalysis
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language:
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Short-container-title:Bull. Chem. React. Eng. Catal.
Author:
Pu Shujin,Zhang Xuan,Huang Han,Yang Chengli,Li Dali,Yang Junfang,Ouyang Jie,Chen Xing,Naseer Sidra,Shi Ruofu
Abstract
In this study, a system of photocatalysis for NAD+ regeneration of enzymatic catalysis was constructed. The optimal conditions for the coupling reaction of photocatalysis and biocatalysis were explored. Blue light was chosen for the efficient reaction and the optimal concentration of VB2 (vitamin B2, riboflavin) was determined. NAD+-dependent (R)-1-phenylethanol dehydrogenase was used in the reaction for transforming (R)-1-phenylethanol to acetophenone. The byproducts of the reaction were just H2O and O2 by means of catalase. The coupling reaction of catalysis and photocatalysis can be used for obtaining (S)-1-phenylethanol through racemization of 1-phenylethanol. Copyright © 2019 BCREC Group. All rights reserved
Publisher
Bulletin of Chemical Reaction Engineering and Catalysis
Subject
Process Chemistry and Technology,Catalysis