Comparative Effect of Nimesulide and??Ibuprofen on the Urinary Levels of??Collagen Type II C-Telopeptide Degradation Products and on the Serum Levels of Hyaluronan and Matrix Metalloproteinases-3 and -13 in??Patients with Flare-Up of Osteoarthritis-Reference-Cited by-同舟云学术

Comparative Effect of Nimesulide and??Ibuprofen on the Urinary Levels of??Collagen Type II C-Telopeptide Degradation Products and on the Serum Levels of Hyaluronan and Matrix Metalloproteinases-3 and -13 in??Patients with Flare-Up of Osteoarthritis

Published:2005 Issue:5 Volume:6 Page:261-271
ISSN:1174-5886
Container-title:Drugs in R & D
language:en
Short-container-title:Drugs in R & D

Author:

Manicourt Daniel-Henri,Bevilacqua Maurizio,Righini Velella,Famaey Jean-Pierre,Devogelaer Jean-Pierre

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference51 articles.

1. Proteolysis of the collagen fibril in osteoarthritis

2. Mechanisms involved in cartilage proteoglycan catabolism

3. Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation

4. Aggrecan degradation in chondrocytes is mediated by reactive oxygen species and protected by antioxidants

5. Evidence Linking Chondrocyte Lipid Peroxidation to Cartilage Matrix Protein Degradation

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