Exosomes derived from MDR cells induce cetuximab resistance in CRC via PI3K/AKT signaling‑mediated Sox2 and PD‑L1 expression

Author:

Wei Zhenzhen1,Wang Ziyuan2,Chai Qiong3,Li Zan1,Zhang Mengjie1,Zhang Yuli1,Zhang Lu4,Tang Qingfeng1,Zhu Huirong5,Sui Hua1

Affiliation:

1. Medical Experiment Center, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201803, P.R. China

2. Department of Pathology, Shuguang Hospital, Shanghai 201203, P.R. China

3. Office of Academic Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, P.R. China

4. Department of Integrated Chinese and Western Medicine, The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, Henan 450008, P.R. China

5. Department of Medical Oncology, Shuguang Hospital, Shanghai 201203, P.R. China

Publisher

Spandidos Publications

Subject

Cancer Research,Immunology and Microbiology (miscellaneous),General Medicine

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