Effects of total saikosaponins on CYP3A4 and CYP1A2 in HepaRG cells

Author:

Tang Yunyan1,Li Hongfang2,Tang Jianhua3,Hu Lei2,Ma Feifei1,Liu Yanmiao2,Tang Fushan2

Affiliation:

1. Department of Pharmacy, Affiliated Meitan People's Hospital of Zunyi Medical University, Zunyi, Guizhou 564100, P.R. China

2. The Key Laboratory of Clinical Pharmacy of Zunyi City, Zunyi Medical University, Zunyi, Guizhou 563006, P.R. China

3. Faculty of Biology, Medicine and Health, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, SK10 4TG, UK

Publisher

Spandidos Publications

Reference59 articles.

1. A systematic review of the active saikosaponins and extracts isolated from Radix Bupleuri and their applications;Yuan;Pharm Biol,2017

2. A new discovery: Total Bupleurum saponin extracts can inhibit the proliferation and induce apoptosis of colon cancer cells by regulating the PI3K/Akt/mTOR pathway;Zhang;J Ethnopharmacol,2022

3. Research progress on Bupleurum marginatum var. stenophyllum;Wang;World Latest Med Info,2019

4. Genus Bupleurum: A review of its phytochemistry, pharmacology and modes of action;Ashour;J Pharm Pharmacol,2011

5. A meta-analysis of clinical efficacy of the Dachaihu decoction plus hypoglycemic medicine on type 2 diabetes mellitus;Liu;Clin J Chin Med,2022

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