Antitumor effect of memantine is related to the formation of the splicing isoform of GLG1, a decoy FGF‑binding protein

Author:

Yamaguchi Fumio1,Hayakawa Sumio2,Kawashima Shota3,Asakura Takayuki1,Oishi Yumiko2

Affiliation:

1. Department of Neurosurgery for Community Health, Nippon Medical School, Tokyo 1138603, Japan

2. Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo 1138603, Japan

3. Faculty of Medicine, Nippon Medical School, Tokyo 1138603, Japan

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology

Reference73 articles.

1. Drug repurposing for the treatment of glioblastoma multiforme;Abbruzzese;J Exp Clin Cancer Res,2017

2. Memantine induces apoptosis and inhibits cell cycle progression in LNCaP prostate cancer cells;Albayrak;Hum Exp Toxicol,2018

3. Alzheimer's drug memantine inhibits metastasis and p-Erk protein expression on 4T1 breast cancer cells;Albayrak;Bratisl Lek Listy,2020

4. Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond;Lipton;Nat Rev Drug Discov,2006

5. NMDA receptor-mediated signaling pathways enhance radiation resistance, survival and migration in glioblastoma cells-a potential target for adjuvant radiotherapy;Müller-Längle;Cancers (Basel),2019

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