DYRK1A suppression attenuates HIF‑1α accumulation and enhances the anti‑liver cancer effects of regorafenib and sorafenib under hypoxic conditions-Reference-Cited by-同舟云学术

DYRK1A suppression attenuates HIF‑1α accumulation and enhances the anti‑liver cancer effects of regorafenib and sorafenib under hypoxic conditions

Published:2022-03-03 Issue:4 Volume:60 Page:
ISSN:1019-6439
Container-title:International Journal of Oncology
language:
Short-container-title:Int J Oncol

Author:

Zhang Chong¹,Wu Lin-Wen¹,Li Zhi-Di¹,Zhang Man-Man¹,Wu Jie²,Du Fei-Hua¹,Zeng Ling-Hui¹,Li Yang-Ling³

Affiliation:

1. Department of Pharmacology, School of Medicine, Zhejiang University City College, Hangzhou, Zhejiang 310015, P.R. China

2. School of Pharmaceutical and Materials Engineering and Institute for Advanced Studies, Taizhou University, Taizhou, Jiangsu 318000, P.R. China

3. Department of Clinical Pharmacology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, P.R. China

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology

Reference35 articles.

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4. An Akt/hypoxia-inducible factor-1alpha/platelet-derived growth factor-BB autocrine loop mediates hypoxia-induced chemoresistance in liver cancer cells and tumorigenic hepatic progenitor cells;Lau;Clin Cancer Res,2009

5. HIF-1alpha and cancer therapy;Koh;Recent Results Cancer Res,2010

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