1. Department of Biomedical and Biotechnological Sciences, University of Catania, I‑95123 Catania, Italy
2. Italian League Against Cancer, Section of Catania, I‑95122 Catania, Italy
3. Department of General Surgery and Medical‑Surgical Specialties, Policlinico‑Vittorio Emanuele Hospital, University of Catania, I‑95123 Catania, Italy
4. Epidemiology and Biostatistics Unit, National Cancer Institute IRCCS Fondazione ‘G. Pascale’, I‑80131 Naples, Italy