Comparison of single copy gene‑based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19‑directed CAR T cells in treated patients-Reference-Cited by-同舟云学术

Comparison of single copy gene‑based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19‑directed CAR T cells in treated patients

Published:2022-03-14 Issue:5 Volume:60 Page:
ISSN:1019-6439
Container-title:International Journal of Oncology
language:
Short-container-title:Int J Oncol

Author:

Schubert Maria-Luisa¹,Berger Carolina²,Kunz Alexander¹,Schmitt Anita¹,Badbaran Anita²,Neuber Brigitte¹,Zeschke Silke²,Wang Lei¹,Riecken Kristoffer²,Hückelhoven‑Krauss Angela¹,Müller Ingo³,Müller‑Tidow Carsten¹,Dreger Peter¹,Kröger Nicolaus²,Ayuk Francis²,Schmitt Michael¹,Fehse Boris²

Affiliation:

1. Department of Internal Medicine V (Hematology/Oncology/Rheumatology), University Hospital Heidelberg, D‑69120 Heidelberg, Germany

2. Department of Stem Cell Transplantation, University Medical Centre Hamburg‑Eppendorf, D‑20246 Hamburg, Germany

3. Department of Pediatric Hematology and Oncology, University Medical Centre Hamburg‑Eppendorf, D‑20246 Hamburg, Germany

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology

Reference38 articles.

1. Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans;Jensen;Biol Blood Marrow Transplant,2010

2. CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients;Savoldo;J Clin Invest,2011

3. Tisagenlecleucel Chimeric antigen receptor (CAR) T-cell therapy for relapsed/refractory children and young adults with acute lymphoblastic leukemia (ALL): Real world experience from the center for international blood and marrow transplant research (CIBMTR) and cellular therapy (CT) registry;Grupp;Blood,2019

4. Tisagenlecleucel Chimeric antigen receptor (CAR) T-cell therapy for adults with diffuse large B-Cell lymphoma (DLBCL): Real world experience from the center for international blood & marrow transplant research (CIBMTR) cellular therapy (CT) registry;Jaglowski;Blood,2019

5. Standard-of-care axicabtagene ciloleucel for relapsed or refractory large B-cell lymphoma: Results from the US lymphoma CAR T Consortium;Nastoupil;J Clin Oncol,2020

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Bioanalytical Methods for Characterization of CAR‐T Cellular Kinetics: Comparison of PCR Assays and Matrices;Clinical Pharmacology & Therapeutics;2023-08-09

2. The Evolving Landscape of Potency Assays;Potency Assays for Advanced Stem Cell Therapy Medicinal Products;2023

3. Molecular monitoring of T-cell kinetics and migration in severe neurotoxicity after real-world CD19-specific chimeric antigen receptor T cell therapy;Haematologica;2022-08-11

4. Clinically Applicable Assessment of Tisagenlecleucel CAR T Cell Treatment by Digital Droplet PCR for Copy Number Variant Assessment;International Journal of Molecular Sciences;2022-07-08