Solamargine induces apoptosis of human renal carcinoma cells via downregulating phosphorylated STAT3 expression

Author:

Huang Shuaishuai1,Sun Minyi1,Ren Yu1,Luo Ting2,Wang Xue3,Weng Guobin3,Cen Dong4

Affiliation:

1. Laboratory of Renal Carcinoma, Ningbo Yinzhou No. 2 Hospital, Urology and Nephrology Institute of Ningbo University, Ningbo, Zhejiang 315100, P.R. China

2. Department of Medical Laboratory, Ningbo Yinzhou No. 2 Hospital, Urology and Nephrology Institute of Ningbo University, Ningbo, Zhejiang 315100, P.R. China

3. Laboratory of Renal Carcinoma, Ningbo Yinzhou No. 2 Hospital, Urology and Nephrology Institute of Ningbo University, Ningbo, Zhejiang 315100, P.R. China

4. Department of Medical Laboratory, Ningbo Yinzhou No. 2 Hospital, Urology and Nephrology Institute of Ningbo University, Ningbo, Zhejiang 315100, P.R. China

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology

Reference41 articles.

1. Cancer statistics, 2020;Siegel;CA Cancer J Clin,2020

2. Renal cancer;Capitanio;Lancet,2016

3. miRNA2055p functions as a tumor suppressor by negatively regulating VEGFA and PI3K/Akt/mTOR signaling in renal carcinoma cells;Huang;Oncol Rep,2019

4. STAT3 signaling in immunity;Hillmer;Cytokine Growth Factor Rev,2016

5. Curcumin inhibits the proliferation and invasion of MG-63 cells through inactivation of the p-JAK2/p-STAT3 pathway;Sun;Onco Targets Ther,2019

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